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2 out of 832,912 Years Active: 2013-2025
Title: The Innovative Contributions of Rebecca Oldham-Haltom
Introduction
Rebecca Oldham-Haltom is a prominent inventor based in Marshall, Wisconsin, known for her significant contributions to the field of nucleic acid detection. With a total of 16 patents to her name, she has made remarkable advancements in real-time PCR assay methods and polymerase activity normalization.
Latest Patents
One of her latest patents is the "Real Time Cleavage Assay," which provides a cleavage-based real-time PCR assay method. This innovative method involves subjecting a reaction mixture, comprising PCR reagents and flap cleavage reagents, to two sets of thermocycling conditions. Notably, no additional reagents are added between the first and second sets of cycles, allowing for the measurement of flap probe cleavage in each cycle of the second set. Another significant patent is focused on "Normalization of Polymerase Activity," which relates to minimizing variability in the activity of DNA polymerases, such as Taq DNA polymerase, across different samples or manufacturing lots.
Career Highlights
Rebecca has worked with notable companies, including Exact Sciences Corporation and Exact Sciences Development Company, LLC. Her work in these organizations has been instrumental in advancing technologies related to nucleic acid detection and diagnostics.
Collaborations
Throughout her career, Rebecca has collaborated with esteemed colleagues, including Graham P. Lidgard and Michael J. Domanico. These collaborations have further enriched her contributions to the field.
Conclusion
Rebecca Oldham-Haltom's innovative work in nucleic acid detection and her numerous patents highlight her significant impact on the scientific community. Her contributions continue to pave the way for advancements in diagnostic technologies.