Rebecca C J Twells

Title: Rebecca C J Twells: Innovator in Genetic Research

Introduction

Rebecca C J Twells is a prominent inventor based in Cambridge, GB. She has made significant contributions to the field of genetic research, particularly in relation to type 1 diabetes and associated diseases. With a total of 2 patents, her work has implications for various medical conditions.

Latest Patents

Twells' latest patents include a method of screening for modulators of LRP5 activity. This invention introduces a novel receptor, LDL-receptor-related protein-5 (LRP-5), along with encoding nucleic acid. The gene is linked to type 1 diabetes, specifically the IDDM susceptibility gene IDDM4. The invention encompasses nucleic acid, coding sequences, oligonucleotide primers and probes, polypeptides, pharmaceutical compositions, and methods for diagnosis or prognosis. It also addresses treatment methods for diseases related to the gene, including autoimmune diseases, viral infections, and diabetes. Another significant patent involves the LDL-receptor, which introduces LDL-receptor related protein-3 (LRP-3) and shares similar applications and implications as her previous work.

Career Highlights

Throughout her career, Twells has worked with notable organizations, including The Wellcome Trust Limited and Merck & Co., Inc. Her research has been pivotal in advancing our understanding of genetic factors in various diseases.

Collaborations

Some of her notable collaborators include John A Todd and John W Hess, who have contributed to her research endeavors.

Conclusion

Rebecca C J Twells is a distinguished inventor whose work in genetic research has the potential to impact the treatment of several diseases. Her innovative patents reflect her commitment to advancing medical science and improving patient outcomes.