Company Filing History:
Years Active: 1991-2010
Title: Razzak Noureldin: Innovator in Chirally Pure Amino Alcohols
Introduction
Razzak Noureldin, an accomplished inventor based in Brossard, Canada, has made significant contributions to the field of chemistry with a focus on amino alcohols. With a total of four patented inventions, his work is paving the way for innovative applications in pharmaceuticals and beyond.
Latest Patents
Noureldin's latest patent involves the production of chirally pure amino alcohol intermediates, derivatives thereof, and their uses. This inventive method outlines a selective approach to preparing a chiral 2S-amino alcohol which proves useful in synthesizing amide sulfonated or acylated compounds with alkyl, substituted aryl, or substituted heteroaryl groups. The process initiates with a reaction between di-tert-butyl diazene-1,2-dicarboxylate and (4S)-4-benzyl-3-[(S)-trifluoromethyl-alkyl substituted alkanoyl]-1,3-oxazolidin-2-one to yield a complex hydrazine derivative. Subsequent reductions and acid treatment lead to the creation of the desired amino alcohol (2S,3S)-2-amino-trifluoro-methyl alkan-1-ol HCl.
Career Highlights
Noureldin’s career features notable tenures at American Home Products Corporation and Wyeth, where he harnessed his expertise to contribute to groundbreaking research and development initiatives. His journey has been marked by a commitment to advancing the science of organic chemistry, particularly in the realm of chiral compounds.
Collaborations
Throughout his career, Razzak Noureldin has had the privilege of collaborating with distinguished colleagues such as John H. Sellstedt and Chia-Cheng Shaw. These partnerships have played a vital role in enhancing the research output and innovation in the projects they have undertaken together.
Conclusion
Razzak Noureldin stands out not only for his inventive prowess but also for his dedication to the advancement of chemical sciences. With a strong portfolio of patents and impactful collaborations, he continues to be a significant figure in the development of chirally pure amino alcohols, promising advancements in various applications in the industry. His contributions are pivotal in driving innovation forward.