Raymond So

Title: The Innovations of Raymond So

Introduction

Raymond So is a notable inventor based in Richmond Hill, Canada. He has made significant contributions to the field of chemistry, particularly in the development of pharmaceutical compounds. With a total of four patents to his name, his work has had a considerable impact on the industry.

Latest Patents

One of Raymond So's latest patents is related to the preparation of cisapride. This compound, known as cis-4-amino-5-chloro-N-1-3-(4-fluoro-phenoxy)propyl-3-methoxy-4-piperidinyl-2-methoxy-benzamide, is synthesized from novel 1-aryloxyalkyl- or 1-aralkyl-3-arylcarbonyloxy-4-oxo-piperidines. The process involves nuclear substituent rearrangement through acyl transfer under animal-forming conditions, resulting in the corresponding 1-aryloxyalkyl- or 1-aralkyl-3-hydroxy-4-lower alkoxy-4-arylamido piperidine. This intermediate can be converted into the final compound, cisapride, through a series of reactions including reduction and methylation.

Another significant patent involves the synthesis of misoprostol, a synthetic prostaglandin-type compound. The process begins with the preparation of organo metallic cuprate complexes that can react with cyclopentenones. This is achieved by reacting an alkyl lithium compound with a cuprous halide, followed by interaction with a vinyl stannane. The careful management of excess alkyl lithium during these reactions is crucial for the successful formation of the organo metallic cuprate complex.

Career Highlights

Raymond So is currently associated with Torcan Chemical Ltd., where he continues to innovate and develop new chemical processes. His expertise in organic chemistry and pharmaceutical development has positioned him as a valuable asset in his field.

Collaborations

Raymond has collaborated with several professionals in his career, including Yee-Fung Lu and Clarke Slemon. These collaborations have contributed to the advancement of his research and the successful development of his patented compounds.

Conclusion

Raymond So's contributions to the field of chemistry, particularly in pharmaceutical innovations, highlight his role as a significant inventor. His patents reflect a deep understanding