Raymond L Fields

Title: Innovations of Raymond L Fields in Peptide Synthesis

Introduction

Raymond L Fields is a notable inventor based in Mount Airy, MD (US). He has made significant contributions to the field of peptide synthesis, particularly through his innovative methods for modifying peptides. His work has implications for various applications, including immunogens, vaccines, and therapeutics.

Latest Patents

Raymond L Fields holds a patent for the "Synthesis of chloroacetyl and bromoacetyl modified peptides." This patent describes a method to incorporate bromoacetyl and chloroacetyl moieties on amino groups of synthetic peptides using an automated peptide synthesizer. The derivatized peptides exhibit favorable reactions with sulfhydryl-containing proteins and peptides with cysteine residues. The process allows for controlled reactions by adjusting the concentrations of starting peptides in neutral pH buffers. Analytical methods such as gel filtration chromatography, reverse phase HPLC, SDS-PAGE, and amino acid analysis are employed to evaluate the polymers or cyclized peptides. The N-bromoacetyl-derivatized peptides have potential uses in various fields, including pharmaceuticals and materials science.

Career Highlights

Raymond L Fields has dedicated his career to advancing the science of peptide synthesis. His innovative approaches have led to the development of new methodologies that enhance the functionality of synthetic peptides. His work is recognized for its potential to impact therapeutic applications significantly.

Collaborations

Raymond has collaborated with notable colleagues, including Frank A Robey and Wolfgang F Lindner. These collaborations have contributed to the advancement of research in peptide synthesis and its applications.

Conclusion

Raymond L Fields is a distinguished inventor whose work in peptide synthesis has opened new avenues for research and application. His innovative methods and collaborative efforts continue to influence the field positively.