Raymond C Trievel

Title: Innovations of Raymond C Trievel

Introduction

Raymond C Trievel is an accomplished inventor based in Ypsilanti, MI (US). He holds a total of 4 patents that reflect his significant contributions to the field of molecular biology and assay development. His work focuses on creating innovative methods and tools for measuring interactions between compounds and proteins.

Latest Patents

One of his latest patents involves the development of fluorescent molecular probes for use in assays that measure test compound competitive binding with SAM-utilizing proteins. This patent outlines methods for forming homogeneous assay mixtures that include target SAM-utilizing proteins, fluorescent detection analytes, and test compounds. The assay methods allow for the measurement of fluorescence polarization (FP) or time-resolved fluorescence resonance energy transfer (TR-FRET) signals, which are indicative of the binding interactions between the test compound and the SAM-utilizing protein.

Another notable patent describes a method for screening a test agent for activity to modulate an oxidative demethylation enzyme. This method includes preparing a test reaction that comprises the enzyme, a substrate, a test agent, and a specific compound. The process allows for the detection of fluorescence, which indicates the reaction of formaldehyde and the compound, thereby providing insights into the activity of the enzyme in the presence of the test agent.

Career Highlights

Raymond has worked with several prominent organizations, including Arbor Assays LLC and the University of Michigan. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Raymond has collaborated with notable colleagues such as Russell Hart and Barbara Scheuer. Their combined expertise has further advanced the research and development of innovative assays and molecular probes.

Conclusion

Raymond C Trievel's contributions to the field of molecular biology through his patents and collaborations highlight his role as a significant inventor. His innovative approaches to assay development continue to impact research and applications in various scientific domains.