Company Filing History:
Years Active: 2010-2019
Title: Innovations by Ravindra N Singh in Spinal Muscular Atrophy Treatment
Introduction
Ravindra N Singh is a notable inventor based in Shrewsbury, MA (US). He has made significant contributions to the field of medical research, particularly in the treatment of spinal muscular atrophy (SMA). With a total of 5 patents to his name, Singh's work focuses on innovative methods to enhance the expression of SMN protein, which is crucial for individuals affected by SMA.
Latest Patents
One of Singh's latest patents involves a groundbreaking approach to treating spinal muscular atrophy by targeting the SMN2 splice site inhibitory sequences. This invention is directed towards methods and compositions that can block the inhibitory effect of an intronic splicing silencer element, known as ISS-N1, located in the SMN2 gene. The compositions include oligonucleotide reagents that effectively target the SMN2 ISS-N1 site in the SMN2 pre-mRNA. By modulating the splicing of SMN2 pre-mRNA to include exon 7 in the processed transcript, these ISS-N1 blocking agents elevate the expression of SMN protein. This is particularly important as it compensates for the loss of SMN protein expression commonly observed in subjects with spinal muscular atrophy.
Career Highlights
Ravindra N Singh is affiliated with the University of Massachusetts, where he continues to advance his research and innovations. His work has garnered attention for its potential to significantly improve the quality of life for individuals suffering from SMA.
Collaborations
Singh collaborates with notable colleagues, including Natalia N Singh and Nirmal K Singh, who contribute to his research endeavors and innovations in the field.
Conclusion
Ravindra N Singh's contributions to the treatment of spinal muscular atrophy through innovative patent developments highlight his commitment to advancing medical science. His work not only showcases his inventive spirit but also holds promise for improving patient outcomes in the future.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.