Randolph L Greasham

Title: The Innovations of Randolph L Greasham

Introduction

Randolph L Greasham is a notable inventor based in Mountainside, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the development of methods that enhance yeast recombinant expression systems. With a total of three patents to his name, Greasham's work has had a meaningful impact on various industries.

Latest Patents

One of his latest patents is a method for improving culture medium for recombinant yeast. This innovation focuses on enhancing yields in yeast recombinant expression systems by identifying subpar lots and supplementing them with a specific combination of adenine, trehalose, and/or lactate. Another significant patent involves the conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomers. This process utilizes a strain of Pseudomonas putida or Rhodococcus sp., followed by various chemical steps, including chiral specific crystallization and treatment with strong acid in the presence of acetonitrile.

Career Highlights

Throughout his career, Greasham has worked with prominent companies such as Merck & Company, Inc. and International Minerals & Chemical Corporation. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research and development projects.

Collaborations

Greasham has collaborated with notable colleagues, including John F Leslie and Matthew H Hulbert. These partnerships have fostered an environment of innovation and have led to the successful development of his patented technologies.

Conclusion

Randolph L Greasham's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to influence advancements in recombinant yeast expression systems and bioconversion processes.