The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 1999
Filed:
Aug. 14, 1996
Barry C Buckland, Westfield, NJ (US);
Neal C Connors, Fanwood, NJ (US);
Michel M Chartrain, Westfield, NJ (US);
Francis P Gailliot, Cranford, NJ (US);
Randolph L Greasham, Mountainside, NJ (US);
Barbara Jackey, Bloomfield, NJ (US);
Brian Heimbuch, North Brunswick, NJ (US);
Chanyong Lee, Princeton, NJ (US);
Roger C Olewinski, Jr, Milltown, NJ (US);
F Edward Roberts, Princeton, NJ (US);
Paul J Reider, Westfield, NJ (US);
Thomas R Verhoeven, Cranford, NJ (US);
Chris H Senanayake, North Brunswick, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
A process is disclosed that bioconverts indene to (1S)-amino-(2R)-indanol substantially free of any of its stereoisomers, by the action of a strain of P. putida or Rhodococcus sp., followed by various chemical step(s), e.g., chiral specific crystallization, treatment with strong acid in the presence of acetonitrile.