Company Filing History:
Years Active: 2007
Title: **Innovative Contributions of Inventor Randall K. Wetzel**
Introduction
Randall K. Wetzel, an accomplished inventor based in Stoneham, MA, has made significant contributions to the field of biotechnology. His pioneering work focuses on antibody development and their applications in cancer treatment. With a keen interest in furthering scientific knowledge, Wetzel holds a notable patent that addresses critical aspects of cancer research.
Latest Patents
Wetzel's key patent, titled "Phospho-specific antibodies to Flt3 and uses thereof," discloses groundbreaking findings related to two newly discovered Flt3 phosphorylation sites: tyrosine 589 (Tyr589) and tyrosine 591 (Tyr591) in the intracellular domain. The patent presents antibodies, both polyclonal and monoclonal, that selectively bind to Flt3 when phosphorylated at these novel sites. This innovation facilitates various assays for determining Flt3 phosphorylation in biological samples. It also aids in identifying patients suitable for Flt3 inhibitor therapy, profiling Flt3 activation in test tissues, and discovering compounds that modulate phosphorylation of Flt3 in test tissues. These contributions are particularly relevant for diagnosing and understanding acute myelogenous leukemia (AML).
Career Highlights
Wetzel is currently associated with Cell Signaling Technology, Inc., a company that is renowned for its focus on developing rigorous tools for research in the life sciences. His work has emphasized the intersection of biotechnology and personalized medicine, enhancing the potential for targeted cancer therapies.
Collaborations
Throughout his career, Wetzel has collaborated with notable colleagues in the field, including Michael Comb and Jiong Wu. These collaborations have fostered an environment of innovation, allowing for significant advancements in antibody research and cancer diagnostics.
Conclusion
In conclusion, Randall K. Wetzel's contributions to the field of biotechnology, particularly through his patented work on phospho-specific antibodies, reflect his commitment to advancing cancer research. His innovative solutions hold promise for improving diagnostic methods and treatment outcomes for patients with cancer. Wetzel’s journey serves as an inspiration to aspiring inventors and researchers aiming to make a meaningful impact in the world of science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.