Ramon John Alabaster

Title: Inventor Profile: Ramon John Alabaster

Introduction

Ramon John Alabaster, an innovative inventor located in Puckeridge, Great Britain, has made significant contributions to the field of chemical synthesis. With a total of two patents to his name, Alabaster is recognized for his expertise and inventive prowess in developing novel chemical processes.

Latest Patents

Alabaster's most notable patent involves a groundbreaking method for the chemical synthesis of a chiral oxazinone. This patent, titled “Chemical Synthesis of a Chiral Oxazinone,” presents a process for the preparation of substantially pure N-benzyl-3-(S)-(4-fluorophenyl)-1,4-oxazin-2-one. The process includes the resolution of α and β isomers of α-pivaloyloxyethyl-(S)-3-(3,6-dihydroxyphenyl)-2-methylalaninate, accomplished through several meticulous steps:

(a) forming the (+) hydrogen tartrate salt of the mixture;

(b) fractionally crystallizing the β-isomer salt; and

(c) recovering the α-isomer from the mother liquor by treatment first with a base and second with a mineral acid.

Career Highlights

Ramon has had a distinguished career, notably working with prominent companies in the pharmaceutical industry such as Merck Sharp & Dohme Corporation and Merck & Company, Inc. His experience in these organizations has undoubtedly contributed to his skills and knowledge, enabling him to thrive as an inventor and scientist.

Collaborations

Throughout his career, Alabaster has collaborated with notable colleagues such as Ian Frank Cottrell and Andrew William Gibson. These partnerships have played a vital role in fostering innovation and advancing their shared objectives in research and development.

Conclusion

Ramon John Alabaster stands out as a dedicated inventor, making substantial advancements in the synthesis of chiral compounds. His patents not only reflect his innovative thinking but also underscore the importance of collaboration in the scientific community. As he continues to push the boundaries of chemical synthesis, Alabaster remains a prominent figure in the landscape of modern inventions.