This inventor holds 8 USPTO granted patents and 7 published patent applications, plus 2 CIPO patents and 3 EPO patents. Top assignee: Fluidigm Corporation. Active years: 2012-2021.
Company Filing History:
Years Active: 2012-2021
Title: Ramesh Ramakrishnan: Innovator in Nucleic Acid Extraction Technologies
Introduction
Ramesh Ramakrishnan is a prominent inventor based in San Jose, CA (US). He has made significant contributions to the field of molecular biology, particularly in the extraction of nucleic acids from biological samples. With a total of 8 patents to his name, Ramakrishnan continues to push the boundaries of innovation in his field.
Latest Patents
One of his latest patents is titled "Methods and kits for extracting nucleic acids from paraffin embedded samples." This invention provides a technology for isolating nucleic acids from wax-embedded samples that is superior to the current state of the art. Standard protocols typically involve dissolving the wax-embedded sample in an organic solvent, extracting nucleic acids into an aqueous buffer, and isolating them. However, Ramakrishnan's technology utilizes hexadecane as the solvent to dissolve the sample, allowing for better yield, less degradation, and more unique mRNA transcripts for subsequent sequencing and analysis.
Another notable patent is the "Method and apparatus for determining copy number variation using digital PCR." This method estimates the concentration of DNA molecules in a biological sample by storing a number of reaction sites in memory and distributing the sample among these sites. The method determines the presence of DNA molecules and computes a confidence interval for the estimated concentration, enhancing the accuracy of DNA quantification.
Career Highlights
Ramesh Ramakrishnan is currently employed at Fluidigm Corporation, where he applies his expertise in molecular biology to develop innovative solutions. His work has significantly impacted the field, particularly in improving the efficiency and accuracy of nucleic acid extraction and quantification.
Collaborations
Some of his notable coworkers include Alain Mir and Simant Dube, who collaborate with him on various projects within Fluidigm Corporation.
Conclusion
Ramesh Ramakrishnan is a distinguished inventor whose work in nucleic acid extraction technologies has advanced the field of molecular biology. His innovative patents reflect his commitment to improving scientific methodologies and enhancing research capabilities.