Company Filing History:
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Years Active: 1995-2001
Title: Ramesh K Prakash: Innovator in Medical Chemistry
Introduction
Ramesh K Prakash is a notable inventor based in Salt Lake City, UT, who has made significant contributions to the field of medical chemistry. With a total of four patents to his name, he has focused on developing innovative solutions for diagnosing and treating various diseases.
Latest Patents
One of his latest patents is titled "Conjugates targeted to the interleukin-2 receptor." This invention involves a composition designed for the intracellular delivery of a chemical agent into interleukin-2-receptor-bearing cells, such as activated T cells. The composition includes a chemical agent and at least one copy of an interleukin-2-receptor-binding and endocytosis-inducing ligand coupled to a water-soluble polymer. The ligand binds to a receptor on the target cell, facilitating the endocytosis of the composition. The chemical agents can include cytotoxins, transforming nucleic acids, gene regulators, labels, antigens, and drugs. A preferred water-soluble polymer for this composition is polyalkylene oxide, such as polyethylene glycol and its activated derivatives. Additionally, the patent discloses methods for using these compositions to deliver chemical agents in vivo or in vitro, as well as a method for detecting diseases associated with elevated levels of soluble IL-2 receptor, including various types of leukemia and lymphoma.
Another significant patent by Ramesh K Prakash is related to a "Recombinant antigen for diagnosing rheumatoid arthritis." This method involves providing a recombinant antigen (RAMA) and detecting rheumatoid arthritis-associated IgM antibodies against the RAMA antigen in patient sera. The RAMA antigen comprises specific sequences and peptides that are substantially homologous. The patent also includes a purified and isolated DNA encoding the RAMA antigen and a transformed host containing this DNA.
Career Highlights
Throughout his career, Ramesh K Prakash has worked with prominent companies in the pharmaceutical industry, including Theratech, Inc. and Watson Laboratories Inc. His work has significantly impacted the development of diagnostic and therapeutic methods in medicine.
Collaborations
Ramesh has collaborated with various professionals in his field, including his coworker Christopher M Clemens, to advance research and innovation in medical chemistry.
Conclusion
Ramesh K Prakash is a distinguished inventor whose work in medical chemistry has led to important