This inventor holds 2 USPTO granted patents. Top assignees: Biotechnica International, Inc., H.j. Heinz Company. Active years: 1988.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
2 out of 12 
1 out of 95 
Years Active: 1988
Title: Ramaswamy Balakrishnan: Innovator in Biotechnology
Introduction
Ramaswamy Balakrishnan is a notable inventor based in Framingham, MA (US). He has made significant contributions to the field of biotechnology, particularly through his innovative patents. With a total of 2 patents, Balakrishnan has focused on advancing genetic engineering and microbial processes.
Latest Patents
His latest patents include groundbreaking work on enzyme deregulation and controlled gene excision. The first patent involves the production of proteins with chorismate mutase-prephenate dehydratase (CMPD) activity, which are engineered to lack phenylalanine sensitivity. These proteins contain a sequence that corresponds to the N-terminal 337 amino acids of Escherichia coli CMPD. The expression vectors used in this process enable the transformation of host microorganisms, which are then cultured to produce phenylalanine.
The second patent addresses the engineering of an Escherichia coli chromosomal DNA segment for controllable excision. This segment includes a gene that determines a function lost in the absence of the chromosomal segment. The design incorporates a pair of lambdoid phage att sites at opposite ends, along with a gene encoding the function. By controlling the excision of this DNA segment, Balakrishnan's invention aims to optimize cell growth and minimize the diversion of intermediates from desired fermentation products.
Career Highlights
Throughout his career, Ramaswamy Balakrishnan has worked with prominent companies in the biotechnology sector. Notable among these are Biotechnica International, Inc. and H.J. Heinz Company. His experience in these organizations has contributed to his expertise and innovative capabilities in the field.
Collaborations
One of his notable collaborators is Keith C. Backman. Their partnership has likely fostered advancements in their respective research areas.
Conclusion
Ramaswamy Balakrishnan's contributions to biotechnology through his patents and career experiences highlight his role as an innovator in the field. His work continues to influence advancements in genetic engineering and microbial processes.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile