Location History:
- San Francisco, CA (US) (2000)
- Rockville, MD (US) (2004 - 2006)
Company Filing History:
Years Active: 2000-2006
Title: Innovations of Ramanujan S Hegde
Introduction
Ramanujan S Hegde is a notable inventor based in Rockville, MD (US). He has made significant contributions to the field of protein regulation, holding a total of 3 patents. His work focuses on the identification and utilization of novel protein conformers, which has implications for drug development and disease treatment.
Latest Patents
One of his latest patents is titled "Conformational and topological protein regulation." This patent provides methods and compositions for identifying novel conformers of proteins that were previously unknown. By employing chimeric genes that replace a native signal sequence with a different one, Ramanujan's methods allow for the production of a conformer. This enables a comparison between the native protein and the product of the chimeric gene. When the conformations differ, the resulting protein can be utilized for various applications, including the production of antibodies, elucidating mechanisms associated with both the native and different conformer proteins, and conducting assays for the presence of the different conformer in physiological samples. Furthermore, this innovation aids in the identification of compounds that specifically bind to the conformer, particularly in the context of drug development. In cases where the formation of the conformer is linked to a diseased state, it can be used in screening processes to identify potential drug candidates.
Career Highlights
Ramanujan S Hegde is affiliated with the University of California, where he continues to advance his research in protein regulation. His work has garnered attention for its potential applications in biotechnology and medicine.
Collaborations
He has collaborated with notable colleagues, including Vishwanath R Lingappa and D Thomas Rutkowski, contributing to a rich environment of innovation and research.
Conclusion
Ramanujan S Hegde's contributions to the field of protein regulation exemplify the impact of innovative research on medicine and biotechnology. His patents reflect a commitment to advancing scientific knowledge and improving health outcomes.