Company Filing History:
2 out of 9 
1 out of 2,921 
Years Active: 1999-2000
Title: Ralph Spindler: Innovator in Dendritic Polymers
Introduction
Ralph Spindler is a notable inventor based in Midland, MI (US), recognized for his contributions to the field of dendritic polymers. With a total of 2 patents, he has made significant advancements in the development of materials with unique properties and applications.
Latest Patents
Spindler's latest patents focus on disulfide-containing dendritic polymers. These polymers contain disulfide functional groups that remain inert under non-reducing conditions but can form sulfhydryl groups when exposed to a reducing agent. The synthesis involves creating dendritic polymers with a core featuring a disulfide linkage or reacting a dendritic polymer with a molecule that has a disulfide linkage and reactive terminal groups. One aspect of his invention provides dendritic polymers with a single disulfide functional group at the core, which can be reduced to yield two sulfhydryl groups. These groups can bind to various molecules, including proteins and oligonucleotides, making them useful in diagnostics, drug delivery, gene therapy, and imaging applications. Additionally, Spindler has developed dendrimer-based nanoscopic sponges and metal composites, which consist of networks capable of acting as sponges for electrophilic guest moieties, yielding novel organo-inorganic composites.
Career Highlights
Throughout his career, Ralph Spindler has worked with prominent companies such as Dendritech Inc. and Dow Corning Corporation. His work has significantly impacted the field of polymer science, particularly in the development of functionalized dendritic polymers.
Collaborations
Spindler has collaborated with notable individuals in his field, including June W Klimash and Herbert M Brothers, II. These collaborations have contributed to the advancement of his research and innovations.
Conclusion
Ralph Spindler's work in dendritic polymers showcases his innovative spirit and dedication to advancing material science. His patents reflect a commitment to developing applications that can benefit various industries, from healthcare to materials engineering.