Rajika Perera

Rajika Perera is a prominent inventor based in Pasadena, California. She has made significant contributions to the field of biotechnology, particularly in the development of polypeptide drugs. With a total of four patents to her name, her work has the potential to impact various therapeutic applications.

Latest Patents

Rajika's latest patents focus on selecting for the developability of polypeptide drugs in eukaryotic cell display systems. One of her notable inventions involves using the surface presentation level of binders, such as antibodies and receptors, on cultured higher eukaryotic cells as a predictive indicator of developability characteristics, including solubility. Additionally, she has developed display libraries of higher eukaryotic cells, such as mammalian cells, which are adapted for screening surface-displayed binders for their developability and affinity for target binding. Her high-throughput screening methods include built-in selection for developability, considering factors like binder solubility and low propensity for non-specific binding. Furthermore, she has engineered FHA domains as binding agents to target molecules, utilizing a library of variants with circular permutations of the FHA domain that maintain the integrity of the beta-sheet scaffold.

Career Highlights

Throughout her career, Rajika has worked with various companies, including Idea Orchard, LLC and Iontas Limited. Her innovative approaches and research have positioned her as a key figure in her field, contributing to advancements in drug development and biotechnology.

Collaborations

Rajika has collaborated with notable professionals in her field, including Michael Longo and John Gerald McCafferty. These collaborations have further enhanced her research and development efforts.

Conclusion

Rajika Perera's contributions to biotechnology and her innovative patents demonstrate her commitment to advancing the field of drug development. Her work continues to pave the way for new therapeutic solutions.