Rajasckharan Somasundaram

Title: Innovations in Cell Migration Monitoring by Rajasckharan Somasundaram

Introduction

Rajasckharan Somasundaram is an accomplished inventor based in West Chester, PA. He has made significant contributions to the field of cellular biology, particularly in the monitoring of cell migration and the identification of cytotoxic T lymphocyte activity. His innovative work has the potential to advance cancer research and treatment.

Latest Patents

Somasundaram holds a patent for "Methods and compositions for monitoring cell migration and identifying clinically relevant cytotoxic T lymphocyte activity." This patent describes a three-dimensional reconstruct model that contains solid layers of collagen and fibroblasts. This model closely mimics the in vivo conditions of patients, preserving the phenotypic and functional characteristics of the cells. The reconstructs can detect cellular migration, including the active migration of cytotoxic T lymphocytes towards tumor cells, which can be measured by detecting tumor cell lysis. Additionally, these reconstructs can identify factors influencing cell migration, such as chemokines and tumor antigens.

Career Highlights

Somasundaram is affiliated with The Wistar Institute, where he conducts his research. His work is pivotal in understanding the dynamics of cell migration and its implications in cancer therapy. His innovative approaches have garnered attention in the scientific community.

Collaborations

Some of his notable coworkers include Dorothee Herlyn and Meenhard Herlyn. Their collaborative efforts contribute to the advancement of research in cellular biology and cancer treatment.

Conclusion

Rajasckharan Somasundaram's contributions to the field of cell migration monitoring represent a significant advancement in cancer research. His innovative patent and work at The Wistar Institute highlight the importance of understanding cellular dynamics in developing effective therapies.