Rafael A Ponce, Jr

Title: Innovations by Rafael A Ponce, Jr.

Introduction

Rafael A Ponce, Jr. is an accomplished inventor based in Seattle, WA (US). He has made significant contributions to the field of autoimmune disease treatment through his innovative patent work. With a total of 2 patents, his inventions focus on novel combination therapies that target specific pathways in the immune system.

Latest Patents

One of his latest patents is titled "Combination of BLyS inhibition and anti-CD 20 agents for treatment of autoimmune disease." This invention relates to therapies that involve the inhibition of BLyS or BLyS/APRIL alongside anti-CD20 agents. The preferred method includes using Fc-fusion proteins, such as TACI-Fc, BAFF-R-Fc, or BCMA-Fc, to reduce B cell levels in patients suffering from autoimmune diseases. Another notable patent is "Combination of BLyS and/or APRIL inhibition and immunosuppressants for treatment of autoimmune disease." This invention also focuses on combination therapies that utilize Fc-fusion proteins and various immunosuppressive drugs, including cyclophosphamide and azathioprine, to reduce immunoglobulin levels in patients.

Career Highlights

Throughout his career, Rafael has worked with notable companies such as Zymogenetics, Inc. and Ares Trading S.a. His experience in these organizations has contributed to his expertise in developing innovative treatments for autoimmune diseases.

Collaborations

Rafael has collaborated with esteemed colleagues, including Hans Otto Lennart Graffner and Sergio Peano. These partnerships have further enhanced his research and development efforts in the field.

Conclusion

Rafael A Ponce, Jr. is a prominent inventor whose work in autoimmune disease therapies showcases his innovative spirit and dedication to improving patient outcomes. His patents reflect a deep understanding of complex biological mechanisms and a commitment to advancing medical science.