Company Filing History:
Years Active: 1998-2009
Title: Innovations of Qinwei Shi in Cardiac Diagnostics
Introduction
Qinwei Shi is a prominent inventor based in Etobicoke, Canada, known for his significant contributions to the field of cardiac diagnostics. With a total of 11 patents to his name, he has made remarkable advancements that enhance the detection and understanding of myocardial infarction.
Latest Patents
Among his latest patents, Shi has developed polypeptides corresponding to stable, circulating degradation products of troponin I (TnI). These fragments include a sequence of the N-terminus of native cardiac TnI with 95-115 amino acids, as well as fragments lacking about 20-30 N-terminal amino acids. The utilities of these fragments and antibodies include sensitive detection of myocardial infarction and purification of antibodies sensitive to the detection of troponin I degradation products. Additionally, he has invented single-chain polypeptides comprising human cardiac troponin I and troponin C. These polypeptides can be expressed recombinantly, with a preferred linker peptide of about 6 to 30 amino acids. This invention has utility as a control or calibrator for troponin assays, for the purification of troponin subunits, and as an antigen for the preparation of antibodies.
Career Highlights
Qinwei Shi is currently associated with Spectral Diagnostics, Inc., where he continues to innovate in the field of cardiac health. His work has been instrumental in developing diagnostic tools that improve patient outcomes and enhance the accuracy of cardiac assessments.
Collaborations
Shi collaborates with notable colleagues, including Shigui Liu and Helmut E Freitag, who contribute to his research and development efforts in cardiac diagnostics.
Conclusion
Qinwei Shi's innovative work in the field of cardiac diagnostics exemplifies the impact of scientific research on healthcare. His patents not only advance the understanding of cardiac conditions but also pave the way for improved diagnostic methods.