The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2009

Filed:

Aug. 29, 2001
Applicants:

Qinwei Shi, Etobicoke, CA;

Shigui Liu, Mississauga, CA;

Mingfu Ling, Toronto, CA;

Inventors:

Qinwei Shi, Etobicoke, CA;

Shigui Liu, Mississauga, CA;

Mingfu Ling, Toronto, CA;

Assignee:

Spectral Diagnostics, Inc, Toronto Ontario, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/38 (2006.01); A61K 45/00 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Polypeptides corresponding to stable, circulating degradation products of troponin I (TnI) are described. The fragments comprise a sequence of the N-terminus of native cardiac TnI with 95-115 amino acid and additionally include fragments lacking about the 20-30 N-terminal amino acids. Utilities of these fragments and antibodies thereto include sensitive detection of myocardial infarction and purification of antibodies sensitive to the detection of troponin I degradation products.


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