Company Filing History:
Years Active: 2003-2013
Title: Innovations of Qiang Liu in Nucleotide Recognition
Introduction
Qiang Liu is a prominent inventor based in Foster City, CA, known for his significant contributions to the field of biotechnology. He holds a total of 16 patents, showcasing his innovative approach to solving complex biological problems. His work primarily focuses on the development of zinc finger proteins for nucleotide recognition.
Latest Patents
One of Qiang Liu's latest patents is titled "Position dependent recognition of GNN nucleotide triplets by zinc fingers." This patent addresses the specificity of binding of zinc fingers to triplet or quadruplet nucleotide target subsites. The binding specificity is influenced by the location of the zinc finger within a multifinger protein and the corresponding target subsite within a larger target sequence. The patent provides optimized zinc finger amino acid sequences for recognizing triplet target subsites that have the nucleotide G in the 5'-most position. This innovation allows for the construction of multi-finger zinc finger proteins with improved affinity and specificity for their target sequences, enhancing their biological activity.
Career Highlights
Throughout his career, Qiang Liu has worked with notable companies in the biotechnology sector, including Sangamo Biosciences, Inc. and Amgen Mountain View, Inc. His experience in these organizations has contributed to his expertise in the development of innovative biotechnological solutions.
Collaborations
Qiang Liu has collaborated with esteemed colleagues such as Edward J Rebar and Andrew Jamieson. These collaborations have further enriched his research and development efforts in the field of nucleotide recognition.
Conclusion
Qiang Liu's innovative work in the recognition of nucleotide triplets through zinc finger proteins exemplifies his significant contributions to biotechnology. His patents and collaborations highlight his commitment to advancing scientific knowledge and technology in this vital area.
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