This inventor holds 4 USPTO granted patents and 1 EPO patent. Top assignee: Council of Scientific and Industrial Research. Active years: 2007-2016.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Delhi, IN (2007 - 2014)
- New Delhi, IN (2016)
Company Filing History:
Years Active: 2007-2016
Title: Puranam Usha Sarma: Innovator in Diagnostic Assays and Eosinophil Modulation
Introduction
Puranam Usha Sarma is a distinguished inventor based in Delhi, India. He has made significant contributions to the field of biotechnology, particularly in the development of diagnostic assays and therapeutic formulations. With a total of 4 patents to his name, his work has the potential to impact both human health and agricultural practices.
Latest Patents
One of his latest patents focuses on diagnostic assays for the detection and identification of aspergilli. Three important species of aspergilli are known to contribute to the pathogenicity of allergic and invasive diseases in humans. They are also recognized as plant pathogens. Several important ESTs and genes of these species have been identified and characterized. However, efforts are still needed to explore 30% of the genes for their valuable products. The polyketide biosynthetic pathway in these species produces important secondary metabolites, including polyketide toxins like Aflatoxins and drugs such as Lovastatins. With the availability of genome sequences, it is now possible to characterize the structure and function of important genes in these species. Based on gene sequence information on PKS enzymes, diagnostic sequences have been identified, leading to the development of a multiplex PCR assay using clinical and agricultural samples.
Another significant invention by Sarma involves the use of surfactant protein-D (SP-D) in modulating the activity of human eosinophils derived from hypereosinophilic patients. This formulation aims to increase the activation state and apoptosis of eosinophils. The utility of this invention can be extended to human subjects in resolving eosinophilic inflammations related to various diseases and disorders, including neuromuscular and respiratory diseases, hypereosinophilic leukemias, and skin diseases.
Career Highlights
Puranam Usha Sarma is affiliated with the Council of Scientific and Industrial Research, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in both medical and agricultural fields.
Collaborations
Sarma has collaborated with notable coworkers, including Taruna Madan and Shweta Saxena, to further enhance the impact of his research.
Conclusion
Puranam Usha Sarma is a prominent inventor whose work in diagnostic assays and eos
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile