Pu Sun

Title: Pu Sun - Innovator in Antibody Preparation

Introduction

Pu Sun is a notable inventor based in Lanzhou, China. He has made significant contributions to the field of antibody preparation, particularly in developing methods to combat foot-and-mouth disease virus.

Latest Patents

Pu Sun holds a patent titled "Method for preparing whole bovine-derived broadly neutralizing antibody against serotype O foot-and-mouth disease virus." This invention relates to a method for preparing a whole bovine-derived broadly neutralizing antibody against the serotype O foot-and-mouth disease virus, which belongs to the technical field of antibody preparation. The method includes several steps: conducting immunization on cattle, screening for serotype O foot-and-mouth disease virus antigen-specific single B cells, amplifying variable region genes of the heavy and light chains, acquiring constant region sequences of the heavy and light chains, preparing a full-length heavy chain vector, co-transfecting a cell, taking the supernatant of cell culture, and purifying. This innovative method utilizes different foot-and-mouth disease virus strains to infect cattle, ultimately obtaining a neutralizing antibody capable of neutralizing three topotypes of serotype O FMDVs.

Career Highlights

Pu Sun is affiliated with the Chinese Academy of Agricultural Sciences, where he conducts his research and development work. His dedication to advancing agricultural sciences has positioned him as a key figure in his field.

Collaborations

He collaborates with esteemed colleagues, including Huifang Bao and Zaixin Liu, to further enhance the research and development of antibody preparation techniques.

Conclusion

Pu Sun's innovative work in antibody preparation showcases his commitment to addressing significant agricultural challenges. His contributions are vital in the ongoing fight against foot-and-mouth disease virus, highlighting the importance of research in public health and agriculture.