This inventor holds 6 USPTO granted patents and 4 published patent applications. Top assignees: University of Medicine and Dentistry of New Jersey, New Jersey Institute of Technology, Rutgers, The State University of New Jersey. Active years: 2005-2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
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Years Active: 2005-2019
Title: Pranela Rameshwar: Innovator in Cancer Research
Introduction
Pranela Rameshwar is a notable inventor based in Maplewood, NJ (US). He has made significant contributions to the field of cancer research, particularly in understanding and treating cancer dormancy. With a total of 6 patents to his name, Rameshwar's work is paving the way for innovative approaches in oncology.
Latest Patents
One of Rameshwar's latest patents is a 3-D in vitro model for breast cancer dormancy. This model is designed to study and treat cancer dormancy effectively. It maintains breast cancer cells in a dormant state, which is crucial for drug discovery. Unlike conventional two-dimensional tissue culture plastic, this 3-D model allows tumor-forming breast cancer cells to remain viable without proliferation. The model includes a fibrous polycaprolactone with 30 wt. % hydroxyapatite, mimicking the structure of bone tissue.
Another significant patent is the method of reversing carboplatin resistance by inhibition of HGFIN. This invention involves the cloning of a new cDNA, HGFIN, from stimulated bone marrow stromal cells. The novel gene encodes a protein receptor that regulates hematopoietic proliferation and differentiation. HGFIN is particularly relevant in treating hyperproliferative disorders, especially bone and breast cancer, as it suppresses proliferating cells.
Career Highlights
Rameshwar has worked with esteemed institutions such as the University of Medicine and Dentistry of New Jersey and the New Jersey Institute of Technology. His research has garnered attention for its innovative approaches to cancer treatment and understanding.
Collaborations
Rameshwar has collaborated with notable colleagues, including Treena Lynne Arinzeh and Khadidiatou T Guiro. Their combined expertise contributes to the advancement of cancer research and treatment methodologies.
Conclusion
Pranela Rameshwar's contributions to cancer research through his innovative patents highlight his commitment to improving treatment options for patients. His work continues to inspire advancements in the field of oncology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile