Pranab K Gupta

Title: Pranab K Gupta: Innovator in Nucleoside Analog Synthesis

Introduction

Pranab K Gupta is a notable inventor based in West Bloomfield, MI (US). He has made significant contributions to the field of chemistry, particularly in the synthesis of nucleoside analogs. His innovative work has implications for drug development and therapeutic applications.

Latest Patents

Pranab K Gupta holds a patent for a process titled "Process for the preparation of 9-β-anomeric nucleoside analogs." This patent describes a method for enhancing the regio and stereoselective synthesis of 9-β-anomeric nucleoside analogs. The process involves the introduction of the sugar moiety onto a 6-substituted purine base, resulting in the exclusive formation of 9-β-D- or L-purine nucleoside analogs. This method allows for the high-yield synthesis of various nucleoside analogs, including 2'-deoxy, 3'-deoxy, 2'-deoxy-2'-β-fluoro, and 2',3'-dideoxy-2'-β-fluoro purine nucleoside analogs, with minimal formation of 7-positional isomers. The compounds produced are either drugs or intermediates for drug development.

Career Highlights

Pranab K Gupta is associated with Ash Stevens, Inc., where he continues to apply his expertise in nucleoside chemistry. His work has been instrumental in advancing the understanding and production of nucleoside analogs, which are crucial in the pharmaceutical industry.

Collaborations

Pranab has collaborated with Stephen A Munk, further enhancing the research and development efforts at Ash Stevens, Inc. Their combined expertise contributes to the innovative projects undertaken by the company.

Conclusion

Pranab K Gupta's contributions to the field of nucleoside analog synthesis highlight his role as an important inventor in the pharmaceutical industry. His patented processes pave the way for advancements in drug development and therapeutic applications.