Company Filing History:
Years Active: 1992-2003
Title: The Innovative Mind of Prabir Bhattacharya
Introduction
Prabir Bhattacharya, an accomplished inventor based in Walnut, California, has made significant contributions to the field of biotechnology. With a total of six patents to his name, his innovative work revolves around enhancing protein therapies through advanced purification and viral inactivation processes.
Latest Patents
Among Bhattacharya's latest patents is a groundbreaking method for the viral inactivation of lyophilized blood proteins. This innovative process focuses on inactivating viral contaminants in lyophilized Factor VIII by utilizing heat. It involves creating a stable complex between Factor VIII and cyclodextrin in an aqueous solution, followed by lyophilization. The resulting complex is heated to a temperature of 60°C, effectively inactivating any viruses present, allowing safe reconstitution before use in patient treatment.
Another notable invention is a process for separating alpha-1-proteinase inhibitor from Cohn fractions IV1 and IV4 paste. This method involves purifying the alpha-1-proteinase inhibitor from an impure protein fraction using polyethylene glycol (PEG) precipitation. The subsequent steps include anion-exchange purification followed by metal chelation, leading to a product with specific activity greater than 0.6 units/mg.
Career Highlights
Prabir Bhattacharya has dedicated his career to the advancement of protein therapeutics. He currently works at Alpha Therapeutic Corporation, a company renowned for its cutting-edge research in blood-derived therapies. His combining of scientific knowledge with practical methodologies has played a crucial role in developing safe and effective treatments for patients requiring factor therapies.
Collaborations
Throughout his career, Bhattacharya has collaborated with several reputed professionals, including Toshiharu Motokubota and Norman M. Fedalizo. Their combined expertise and innovative approach have further enhanced the quality and efficiency of their research initiatives.
Conclusion
Prabir Bhattacharya exemplifies innovation in the field of biotechnology, with his significant contributions protecting and improving patient health through advanced purification and viral inactivation techniques. His work not only impacts the scientific community but also stands to revolutionize therapies involving blood proteins, showcasing the importance of innovation in medicine.