Pouneh Dokouhaki

Title: Pouneh Dokouhaki: Innovator in T Cell Expansion Methods

Introduction

Pouneh Dokouhaki is a notable inventor based in Oakville, CA. She has made significant contributions to the field of immunology, particularly in the expansion of double negative T cells. With a total of 2 patents, her work is paving the way for advancements in cancer treatment and autoimmune diseases.

Latest Patents

One of her latest patents describes a method of expanding double negative T cells in culture. The method involves several steps: providing a starting sample comprising DN T cells or their precursors, substantially depleting CD8 and CD4 T cells from the sample, and culturing the sample with an immobilized T cell mitogen in a growth-stimulating culture medium. Following this, the cells are washed and resuspended in a culture medium without the T cell mitogen, and then washed again before being resuspended in a medium containing both the growth agent and a soluble T cell mitogen. The DN T cells obtained through this method have potential applications in treating cancer, infectious diseases, graft versus host disease, and autoimmune diseases.

Career Highlights

Pouneh Dokouhaki is affiliated with the University Health Network, where she continues her research and development in T cell therapies. Her innovative approaches have garnered attention in the scientific community, contributing to the advancement of immunological treatments.

Collaborations

She collaborates with esteemed colleagues such as Mei Han and Li Zhang, who share her commitment to advancing medical science through innovative research.

Conclusion

Pouneh Dokouhaki's work in expanding double negative T cells represents a significant advancement in immunology. Her contributions are vital for developing new therapies for various diseases, showcasing her role as a leading inventor in this field.