Po-Wei Lee

Title: Innovations of Po-Wei Lee: A Journey in Biodegradable Nanoparticles

Introduction

Po-Wei Lee, an innovative inventor from Jhonghe, Taiwan, has made significant contributions to the field of biomedicine through his groundbreaking patents. With a total of three patents under his name, his work focuses primarily on the development and application of biodegradable nanoparticles for protein and nucleic acid delivery.

Latest Patents

Among Po-Wei Lee's notable inventions is the patent titled "Nanoparticles for Protein/Peptide Delivery and Delivery Means Thereof." This invention outlines the use of biodegradable nanoparticles designed for projectile bombardment as carriers for administering proteins, peptides, or siRNAs transdermally to animal subjects. The nanoparticles are constructed with a positively charged chitosan substrate, which is paired with a negatively charged core substrate complexed with chitosan, all while encapsulating bioactive agents.

In addition, he has developed another patent dealing with similar technology for RNA delivery, titled "Nanoparticles for Protein/Peptide Delivery and Delivery Means Thereof." This innovation also features biodegradable nanoparticles meant to deliver nucleic acids, such as DNA, RNA, or siRNAs transdermally. The design ensures efficient encapsulation of nucleic acid within the nanoparticles or loading it electrostatically onto their exterior surface.

Career Highlights

Po-Wei Lee's career has been marked by his impactful work at prominent organizations. He has held positions at Gp Medical, Inc. and the National Tsing Hua University, where he has contributed significantly to research and development efforts in the area of nanotechnology and drug delivery systems.

Collaborations

Throughout his career, Po-Wei Lee has collaborated with various esteemed professionals in his field, including notable coworkers such as Hsing-Wen Sung and Mei-Chin Chen. These partnerships have played a vital role in refining his innovations and advancing the research surrounding biodegradable nanoparticles.

Conclusion

Po-Wei Lee's inventive spirit and dedication to advancing biomedicine through nanoparticles mark him as a key figure in his field. His work on biodegradable nanoparticles for transdermal delivery of proteins and nucleic acids demonstrates a promising future for therapeutic applications, demonstrating the vital link between innovative ideas and practical medical solutions.