Pius Spielhofer

Title: Pius Spielhofer: Innovator in RNA Virus Methodology

Introduction

Pius Spielhofer is a notable inventor based in Buron, Switzerland. He has made significant contributions to the field of virology, particularly in the development of methodologies for generating nonsegmented negative-strand RNA viruses. With a total of 4 patents, his work has implications for vaccine development and gene therapy applications.

Latest Patents

Spielhofer's latest patents include a groundbreaking invention related to cDNA corresponding to the antigenome of nonsegmented negative-strand RNA viruses. This invention outlines a methodology for generating these viruses from cloned deoxyribonucleic acid (cDNA). The rescued viruses produced through this process are suitable for use as vaccines or as plasmids in somatic gene therapy applications. Additionally, the invention encompasses cDNA molecules that serve as tools in this methodology and helper cell lines that facilitate the direct rescue of such viruses. Measles virus (MV) is utilized as a model for other representatives of the Mononegavirales, particularly within the family Paramyxoviridae.

Career Highlights

Throughout his career, Pius Spielhofer has worked with several prominent companies, including Crucell Switzerland AG and the Swiss Serum and Vaccine Institute in Bern. His expertise in virology and innovative methodologies has positioned him as a key figure in the field.

Collaborations

Spielhofer has collaborated with notable professionals in his field, including Martin Billeter and Frank Radecke. These collaborations have further enhanced his research and contributions to virology.

Conclusion

Pius Spielhofer's innovative work in the development of methodologies for RNA viruses has significant implications for vaccine and gene therapy advancements. His contributions continue to influence the field of virology and highlight the importance of innovation in medical research.