Ping Li

Title: Innovations of Ping Li in Transgenic Research

Introduction

Ping Li is a notable inventor based in Wellesley, MA (US). He has made significant contributions to the field of transgenic research, particularly in the development of genetically modified organisms. His work focuses on the functional disruption of specific genes to better understand their roles in disease and treatment.

Latest Patents

Ping Li holds a patent for a transgenic knockout mouse that has a functionally disrupted interleukin-1.beta. gene. This innovative mouse model is designed to aid in the evaluation of ICE inhibitors and to identify disease conditions that can be treated with these inhibitors. The patent describes a mouse that may be heterozygous or homozygous for the ICE gene disruption, with homozygous mice showing substantially reduced secretion of mature interleukin-1.beta. and interleukin-1.alpha. compared to non-mutant mice. This invention also includes nucleic acid constructs and recombinant vectors for disrupting the ICE gene in host cells.

Career Highlights

Ping Li is associated with BASF Aktiengesellschaft, where he continues to advance his research in transgenic technology. His work has implications for understanding immune responses and developing therapeutic strategies.

Collaborations

He has collaborated with notable colleagues such as Hamish John Allen and Subhashis Banerjee, contributing to a rich environment of innovation and research.

Conclusion

Ping Li's contributions to transgenic research, particularly through his patented innovations, highlight the importance of genetic engineering in medical research. His work continues to pave the way for advancements in understanding and treating various diseases.