Company Filing History:
Years Active: 2002-2004
Title: Pierre Van Der Bruggan: Innovator in Cancer Research
Introduction
Pierre Van Der Bruggan is a notable inventor based in Brussels, Belgium. He has made significant contributions to the field of cancer research, particularly through his innovative patents. With a total of 2 patents, his work focuses on the development of peptides and methods for diagnosing and treating cancer.
Latest Patents
One of his latest patents is titled "Mage-A3 peptides presented by HLA class molecules." This invention describes HLA class II binding peptides encoded by the MAGE-A3 tumor-associated gene. It also includes nucleic acids encoding such peptides and related antibodies. The peptides are designed to stimulate the activity and proliferation of CD4 T lymphocytes. Additionally, methods and products are provided for diagnosing and treating conditions characterized by the expression of the MAGE-A3 gene.
Another significant patent is "Tumor antigens and CTL clones isolated by a novel procedure." This invention relates to the isolation of cytotoxic T lymphocyte (CTL) clones that are specific for MAGE-1 and MAGE-4. The CTL clones have been isolated through successive steps of stimulation and testing of lymphocytes with antigen-presenting cells. These cells present antigens derived from various expression systems, including recombinant Yersinia, recombinant Salmonella, or recombinant viruses. The invention also encompasses the MAGE-1 and MAGE-4 antigenic peptides and the peptide/HLA complexes recognized by the isolated CTL clones.
Career Highlights
Throughout his career, Pierre Van Der Bruggan has worked with esteemed organizations, including the Ludwig Institute for Cancer Research Limited. His work has been pivotal in advancing the understanding of tumor antigens and their role in cancer treatment.
Collaborations
Pierre has collaborated with notable colleagues such as Vincent Stroobant and Rosalie Luiten. Their combined efforts have contributed to the success of various research projects and innovations in the field.
Conclusion
Pierre Van Der Bruggan's contributions to cancer research through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in cancer diagnosis and treatment.