Pierre Legrain

Title: Pierre Legrain: Innovator in HIV Research

Introduction

Pierre Legrain is a notable inventor based in Paris, France. He has made significant contributions to the field of HIV research, holding a total of 7 patents. His work focuses on understanding protein-protein interactions that are crucial in the fight against AIDS.

Latest Patents

Among his latest patents, Pierre Legrain has developed innovative methods related to the Human Immunodeficiency Virus (HIV) integrase. One of his patents addresses the interactions between HIV integrase and Transportin, as well as the SR protein. This invention explores the complexes of polypeptides or polynucleotides encoding these proteins, fragments of the polypeptides, and antibodies to the complexes. It also identifies Selected Interacting Domains (SID®) that arise from these interactions. Furthermore, he has patented methods for screening drugs that can modulate these protein interactions, along with pharmaceutical compositions designed for this purpose. Another significant patent involves the interactions between HIV integrase and the LEDGF p75 isoform, further contributing to the understanding of AIDS-related protein interactions.

Career Highlights

Pierre Legrain has worked with prestigious organizations such as Institut Pasteur and Hybrigenics. His research has been pivotal in advancing the scientific community's understanding of HIV and its mechanisms.

Collaborations

Throughout his career, Pierre has collaborated with esteemed colleagues, including Jean-Christophe Rain and Micheline Fromont. These partnerships have enriched his research and contributed to his innovative work in the field.

Conclusion

Pierre Legrain's contributions to HIV research through his patents and collaborations highlight his role as a significant inventor in the scientific community. His work continues to pave the way for advancements in understanding and treating AIDS.