Pierre-Alain Burnouf

Title: Innovations of Pierre-Alain Burnouf in Liposomal Drug Delivery

Introduction

Pierre-Alain Burnouf is a notable inventor based in Taipei, Taiwan. He has made significant contributions to the field of drug delivery systems, particularly through his innovative methods for encapsulating hydrophilic glucuronides in liposomes. His work aims to enhance the efficacy of drug delivery, especially in cancer treatment.

Latest Patents

Burnouf holds a patent for an "Esterification/saponification-based method for liposomal encapsulation of hydrophilic glucuronides." This patent describes a method for loading hydrophilic compounds into liposomes by first adding an alkylester group to form an esterified compound. After the loading process, the alkylester is hydrolyzed to regenerate the hydrophilic compound within the liposomes. Additionally, the method allows for the loading of drugs in a glucuronide methylester form, which is then saponified to a glucuronide form inside the liposomes, improving drug retention. This innovative approach can be particularly beneficial for delivering drugs to tumors in cancer therapy.

Career Highlights

Pierre-Alain Burnouf is affiliated with Academia Sinica, a prestigious research institution in Taiwan. His work has garnered attention for its potential applications in improving drug delivery systems, making significant strides in the pharmaceutical field.

Collaborations

Burnouf collaborates with Steve R Roffler, a fellow researcher, to further explore and develop innovative drug delivery methods.

Conclusion

Pierre-Alain Burnouf's contributions to liposomal drug delivery represent a significant advancement in the field of pharmaceuticals. His innovative methods have the potential to improve treatment outcomes for patients, particularly in oncology.