Philip J Krape

Title: The Innovations of Philip J Krape

Introduction

Philip J Krape is an accomplished inventor based in Wilmington, Delaware. He is known for his significant contributions to the pharmaceutical industry, particularly in the development of processes that enhance drug solubility.

Latest Patents

Krape holds a patent for a process for manufacturing paroxetine solid dispersions. This innovative method involves creating solid dispersions of poorly soluble drugs using either a solvent or fusion process. The patent specifically addresses the preparation of paroxetine free base, combined with an oil, which allows for a low-temperature fusion process. This technique reduces the volume of organic solvents required and facilitates the formation of a paroxetine salt during the manufacturing process.

Career Highlights

Krape's career is marked by his work at Endo Pharmaceuticals Inc., where he has made significant strides in pharmaceutical manufacturing. His expertise in drug formulation has contributed to advancements in the delivery of medications.

Collaborations

Throughout his career, Krape has collaborated with notable colleagues, including Sou-Chan Chang and William A Hein, II. These partnerships have fostered innovation and development in the field of pharmaceuticals.

Conclusion

Philip J Krape's contributions to the pharmaceutical industry, particularly through his patent for paroxetine solid dispersions, highlight his role as a key innovator. His work continues to impact drug formulation and delivery methods.