Company Filing History:
Years Active: 1989-1994
Title: The Innovations of Philip E Thorpe
Introduction
Philip E Thorpe is a notable inventor based in London, GB. He has made significant contributions to the field of immunotoxins, holding a total of 2 patents. His work focuses on enhancing the efficacy of immunotoxins that target tumor-associated antigens.
Latest Patents
Thorpe's latest patents include innovative approaches to disulfide linked immunotoxins. One of his patents discusses the efficacy of immunotoxins that utilize an antibody recognizing a tumor-associated antigen linked to a cytotoxin through a heterobifunctional agent of the disulfide type. The improvement in efficacy is achieved by incorporating a molecular grouping that creates steric hindrance in relation to the disulfide link. This steric hindrance can be provided by a methyl substituted methylene group located in the heterobifunctional link adjacent to the disulfide bond. Another patent elaborates on heterobifunctional linking agents derived from similar principles, further emphasizing the importance of steric hindrance in enhancing immunotoxin effectiveness.
Career Highlights
Philip E Thorpe is associated with ICRF Patents Limited, where he continues to innovate in the field of immunology. His work has garnered attention for its potential applications in cancer treatment, showcasing his commitment to advancing medical science.
Conclusion
Philip E Thorpe's contributions to the field of immunotoxins reflect his dedication to improving cancer therapies. His innovative patents demonstrate the potential for significant advancements in targeted treatments.