Company Filing History:
Years Active: 1996
Title: The Innovative Contributions of Philip Bentley
Introduction
Philip Bentley is a notable inventor based in Bracknell, GB. He has made significant contributions to the field of immunology through his innovative research and patenting efforts. His work focuses on the development of novel compounds that enhance the understanding and treatment of various biological processes.
Latest Patents
Philip Bentley holds a patent for an "Immunogenic ryanodine derivative and related uses." This patent discloses a novel photo-activatable derivative of ryanodine, specifically 9-hydroxy-21-(4-azidobenzoyloxy)-9-epiryanodine. The derivative has been conjugated to keyhole limpet hemocyanin (KLH) to produce antibodies with high affinity and specificity to ryanodine. A radioimmunoassay specific for ryanodine was developed using these anti-ryanodine antibodies, determining a dissociation constant for ryanodine of 1 nM. Additionally, the binding of a labeled, photoactivatable derivative of ryanodine (ABRy) with the ryanodine receptor of skeletal, cardiac, and brain membranes was disclosed. The digestion of the labeled ryanodine receptor revealed a labeled 76 kDa tryptic fragment, which is critical for the formation of the high-affinity ryanodine binding site.
Career Highlights
Philip Bentley is associated with the University of Iowa Research Foundation, where he has contributed to various research initiatives. His work has been instrumental in advancing the understanding of ryanodine and its implications in biological systems. Bentley's innovative approach has garnered attention in the scientific community, leading to further exploration of his findings.
Collaborations
Some of his notable coworkers include Kevin P Campbell and Derrick R Witcher. Their collaborative efforts have enhanced the research output and innovation within their field.
Conclusion
Philip Bentley's contributions to the field of immunology through his patent on ryanodine derivatives exemplify the impact of innovative research on scientific advancement. His work continues to inspire further exploration and development in this critical area of study.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.