This inventor holds 1 USPTO granted patent and 2 published patent applications and 1 EPO patent. Top assignees: Mallinckrodt Enterprises LLC, Mallinckrodt Pharma IP Trading Unlimited Company, Mallinckrodt Pharmaceuticals Ireland Limited. Active years: 2025.
Company Filing History:



Years Active: 2025
Title: Petya Apostolova: Innovator in Immunotherapy
Introduction
Petya Apostolova is a prominent inventor based in Freiburg, Germany. She has made significant contributions to the field of immunotherapy, particularly in the development of methods for generating immunoregulatory cells. Her innovative work aims to improve treatment outcomes for patients undergoing checkpoint-inhibitor therapy.
Latest Patents
Apostolova holds a patent for a method titled "Method for generating immunoregulatory cells in a blood-derived sample." This invention involves a process that includes providing a sample derived from a blood sample of a subject who has received checkpoint-inhibitor therapy and is suspected of developing immune-related adverse events (irAE). The method entails adding a photosensitizing agent, specifically 8-methoxypsoralen, to the sample and subjecting it to UVA irradiation. This process generates immunoregulatory NK cells, which can be utilized in the treatment and prevention of irAE in patients.
Career Highlights
Petya Apostolova is currently employed at Mallinckrodt Pharmaceuticals Ireland Limited, where she continues to advance her research in immunotherapy. Her work is pivotal in addressing the challenges faced by patients receiving checkpoint-inhibitor therapies.
Collaborations
Throughout her career, Apostolova has collaborated with esteemed colleagues, including Robert Zeiser and Justus Duyster. These partnerships have enhanced her research and contributed to the development of innovative therapeutic methods.
Conclusion
Petya Apostolova's contributions to immunotherapy through her patented methods demonstrate her commitment to improving patient care. Her work is a testament to the importance of innovation in the medical field.