Peter W Laird

Title: Inventor Spotlight: Peter W. Laird from South Pasadena, CA

Introduction

Peter W. Laird, an accomplished inventor based in South Pasadena, California, has made significant contributions to the field of DNA research, particularly in the realm of DNA methylation analysis. He holds a total of 10 patents, reflecting his innovative approach towards genetic evaluation and disease diagnosis.

Latest Patents

Among his latest inventions, Laird has developed a high-throughput method of DNA methylation haplotyping. This innovative technique quantifies DNA methylation at a single-base resolution in an allele-specific manner. The method utilizes allele-specific sequence polymorphisms in close proximity to CpG methylation sites, enabling the differentiation of methylation levels between two alleles. Through processes such as bisulfite modification and allele-specific pyrosequencing, the percentage of methylation can be accurately determined, contributing to significant insights in areas like X-inactivation and gene expression regulation.

In addition, Laird introduced the concept of Digital MethyLight, offering sensitive assays for methylation detection by compartmentalizing bisulfite-treated genomic DNA. This approach involves analyzing biological fluids for applications in cancer diagnosis and prognosis, showcasing its utility in clinical settings. His work also includes the development of methods for diagnosing breast cancer using specific gene markers.

Career Highlights

Throughout his career, Peter W. Laird has been affiliated with prominent research institutions, notably the University of Southern California, where he collaborated with various cutting-edge research initiatives. His role at the USC Stevens Center for Innovation has played a crucial part in advancing numerous scientific projects, promoting innovation in genetic research.

Collaborations

Laird's collaborative efforts include working alongside esteemed colleagues such as Kathleen D. Danenberg and Mihaela Campan. Their combined expertise has significantly enhanced the development of novel methodologies in DNA analysis, fostering a collaborative environment aimed at pushing the boundaries of genetic research.

Conclusion

Peter W. Laird's advancements in DNA methylation methods underline his position as a leading inventor in genetic research. His dedication to innovation and collaboration positions him as a pivotal figure within his field, making valuable contributions that will impact both scientific understanding and practical applications in medicine. His legacy continues to inspire future advancements in DNA analysis technologies.