Peter McPherson

Title: Inventor Profile: Peter McPherson

Introduction

Peter McPherson, an innovative inventor based in Branford, CT, has made significant contributions to the field of biochemistry with his groundbreaking patent. With a keen focus on immunogenic compounds, McPherson has developed a novel photo-activatable derivative of ryanodine that holds promise for antibody production and research applications.

Latest Patents

McPherson's notable patent is titled "Immunogenic ryanodine derivative and related uses." This invention describes a unique derivative of ryanodine, specifically 9-hydroxy-21-(4-azidobenzoyloxy)-9-epiryanodine. The compound is conjugated with keyhole limpet hemocyanin (KLH), facilitating the creation of antibodies with high affinity and specificity for ryanodine. Furthermore, a specialized radioimmunoassay has been developed utilizing these anti-ryanodine antibodies, resulting in a dissociation constant for ryanodine of 1 nM. His work also details the interaction of a labeled, photoactivatable ryanodine derivative with ryanodine receptors across skeletal, cardiac, and brain membranes, highlighting the importance of a 76 kDa tryptic fragment in forming high-affinity binding sites.

Career Highlights

Peter McPherson is associated with the University of Iowa Research Foundation, where he has leveraged his expertise in biochemistry and immunology to drive research forward. His pioneering patent reflects a substantial advancement in understanding ryanodine's role within various biological systems, showcasing his dedication to scientific discovery and innovation.

Collaborations

Throughout his career, McPherson has collaborated with notable colleagues, including Kevin P Campbell and Derrick R Witcher. Their combined expertise enhances the research and development of novel immunogenic compounds and their applications, contributing to the growing body of knowledge in the field.

Conclusion

With his innovative approach and impactful research, Peter McPherson stands out as an inventor who is shaping the future of immunology and biochemistry. His contributions, particularly through his patent on the immunogenic ryanodine derivative, underscore the significance of his work in advancing scientific understanding and medical applications. As he continues to collaborate with fellow researchers, McPherson's inventions may lead to new therapeutic avenues and innovations in the biomedical field.