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1 out of 22 Years Active: 2009-2019
Title: Innovations of Peter Kretschmer
Introduction
Peter Kretschmer is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of biotechnology, particularly in the development of variant Factor VIII polypeptides. With a total of four patents to his name, Kretschmer's work has the potential to impact therapeutic approaches for hemophilia and related disorders.
Latest Patents
Kretschmer's latest patents focus on variant Factor VIII polypeptides and methods of their production and use. This disclosure relates to polypeptides that include amino acid substitutions at one or more positions within the thrombin cleavage site and the activation loop. In certain embodiments, these polypeptides comprise substitutions within both the thrombin cleavage site and the activation loop. Further embodiments include substitutions within the A1-A2 domain interface and the A2-A3 domain interface. The disclosure also covers methods for producing and utilizing these variant Factor VIII polypeptides, as well as nucleic acids encoding them, vectors, recombinant cells, tissues, or organisms containing such nucleic acids, and kits and pharmaceutical compositions that include these polypeptides and/or nucleic acids.
Career Highlights
Throughout his career, Kretschmer has worked with prominent companies in the biotechnology sector, including Bayer Healthcare LLC and Bayer Schering Pharma AG. His experience in these organizations has allowed him to collaborate on various innovative projects that advance medical science.
Collaborations
Kretschmer has collaborated with notable professionals in his field, including Terry Hermiston and Fang Jin. These partnerships have contributed to the development of his patented technologies and have fostered a collaborative environment for innovation.
Conclusion
Peter Kretschmer's contributions to the field of biotechnology through his patents on variant Factor VIII polypeptides demonstrate his commitment to advancing medical science. His work has the potential to significantly impact therapeutic strategies for hemophilia and related conditions.