Peter Koulen

Title: Innovations by Inventor Peter Koulen

Introduction

Peter Koulen is a notable inventor based in Leawood, Kansas, with a remarkable portfolio of seven patents. His work primarily focuses on advancements in medical technology, particularly in the fields of cancer detection and cryopreservation.

Latest Patents

One of his latest innovations is a portable photonic sensor system designed as an early detection tool for ovarian cancer. This guided mode resonance (GMR) sensor can simultaneously detect a variety of analytes. It provides a diagnostic system capable of rapidly identifying an array of biomarker proteins in patient samples, such as blood, serum, or plasma. This technology allows for a differential analysis of proteins, enabling the discrimination between early and late stages of disease, including metastatic versus primary ovarian serous carcinomas. The GMR sensor is designed to be compact and portable, enhancing its usability in clinical settings.

Another significant patent is an efficient cryopreservation device that prevents direct contact between biological samples and extracellular ice. This cryoprotective device safeguards aqueous biological materials from mechanical damage caused by ice formation during cryogenic freezing and storage. It achieves this by preventing large ice crystals from coming into contact with the biological material, thus protecting it from damage. The device features a housing with an internal cavity that receives a freezable medium containing the biological material, along with a semi-permeable membrane that blocks larger ice crystals.

Career Highlights

Peter Koulen has contributed to significant advancements in his field through his work at the University of Missouri and City University of New York. His research has focused on developing innovative solutions that address critical challenges in medical diagnostics and preservation.

Collaborations

Throughout his career, Peter has collaborated with notable colleagues, including Xu Han and George John. These partnerships have fostered a collaborative environment that has led to groundbreaking innovations.

Conclusion

Peter Koulen's contributions to the fields of medical technology and cryopreservation highlight his role as a leading inventor. His innovative patents reflect a commitment to improving diagnostic tools and preserving biological materials, ultimately benefiting the medical community and patients alike.