Peter K Working is a notable inventor based in Burlingame, CA (US). He has made significant contributions to the field of pharmaceutical technology, particularly in the development of liposome-entrapped topoisomerase inhibitors. With a total of 4 patents to his name, his work has the potential to impact therapeutic approaches in cancer treatment.

Latest Patents

One of Peter K Working's latest patents focuses on liposome-entrapped topoisomerase inhibitors. This composition is designed for the administration of a therapeutically effective dose of a topoisomerase inhibitor I or a topoisomerase I/II inhibitor. The innovative composition includes liposomes that have an outer surface and an inner surface, defining an aqueous liposome compartment. These liposomes are composed of a vesicle-forming lipid and a vesicle-forming lipid that is derivatized with a hydrophilic polymer. This results in a coating of hydrophilic polymer chains on both the inner and outer surfaces of the liposomes. The topoisomerase inhibitor is entrapped in the liposomes at a concentration of at least about 0.10 μmole drug per μmole lipid.

Career Highlights

Peter K Working has been associated with Alza Corporation, where he has contributed to various innovative projects. His expertise in liposome technology has positioned him as a key figure in the development of advanced pharmaceutical formulations.

Collaborations

Throughout his career, Peter has collaborated with notable colleagues, including James L Slater and Gail T Colbern. These collaborations have further enhanced the impact of his work in the field of pharmaceutical sciences.

Conclusion

Peter K Working's contributions to liposome technology and his innovative patents reflect his dedication to advancing therapeutic solutions. His work continues to influence the pharmaceutical industry and offers promising avenues for future research and development.