Location History:
- Ann Arbor, MI (US) (1998 - 2002)
- Falcon Heights, MN (US) (2006)
Company Filing History:
Years Active: 1998-2006
Title: The Innovations of Peter J Polverini
Introduction
Peter J Polverini is a notable inventor based in Falcon Heights, MN (US). He has made significant contributions to the field of medical research, particularly in the area of viral infections and angiogenesis. With a total of 4 patents, his work has had a profound impact on the understanding and treatment of various diseases.
Latest Patents
Polverini's latest patents include innovative methods for inhibiting HIV replication using small molecule inhibitors. These methods focus on suppressing viral replication in infected host cells by administering compounds that interfere with the binding of C-X-C chemokines to their receptors. This approach is particularly advantageous for treating infections caused by the human immunodeficiency virus. Another significant patent involves the role of CXC chemokines as regulators of angiogenesis. This patent discloses discoveries regarding the angiogenic and angiostatic properties of CXC chemokines, highlighting the ELR motif's control over their ability to induce angiogenesis. Notably, it identifies IP-10, MIG, and certain IL-8 analogues as angiostatic agents, which can be utilized to inhibit angiogenesis in various systems.
Career Highlights
Polverini is affiliated with the University of Michigan, where he continues to advance his research and innovations. His work has garnered attention in the scientific community, contributing to the understanding of complex biological processes and potential therapeutic interventions.
Collaborations
Throughout his career, Polverini has collaborated with esteemed colleagues, including Robert M Strieter and Steven L Kunkel. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Peter J Polverini's contributions to medical research through his patents and collaborations have significantly advanced the understanding of viral infections and angiogenesis. His innovative approaches continue to inspire future research in these critical areas.