Location History:
- Boston, MA (US) (2014)
- Providence, RI (US) (2012 - 2017)
Company Filing History:
Years Active: 2012-2017
Title: The Innovations of Peter H Goldstein
Introduction
Peter H Goldstein is a notable inventor based in Providence, RI (US). He has made significant contributions to the field of biomolecular sequencing, holding a total of 5 patents. His work focuses on developing advanced methods for sequencing biomolecules, which have the potential to revolutionize genetic research and diagnostics.
Latest Patents
Goldstein's latest patents include innovative methods for sequencing a biomolecule by detecting the relative positions of hybridized probes. This sequencing method involves hybridizing a biomolecule with a specially chosen pool of different probes that can be electrically distinguished. The probes are tagged to allow differentiation in a Hybridization Assisted Nanopore Sequencing (HANS) detection system, enabling the determination of their relative positions as the biomolecule passes through a pore or channel. This approach effectively eliminates or greatly reduces ambiguities encountered in previous sequencing methods.
Another significant patent by Goldstein is related to biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment. This method involves forming local ternary complexes along the length of a double-stranded biopolymer target molecule using one or more probes. Information about the location of the probes is obtained using a detector, offering particular advantages when implemented with nanopore detection systems.
Career Highlights
Throughout his career, Goldstein has worked with prominent organizations such as Nabsys, Inc. and the Massachusetts Institute of Technology. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of Goldstein's notable coworkers include Franco Preparata and John S Oliver. Their collaborative efforts have further advanced the research and development of innovative sequencing technologies.
Conclusion
Peter H Goldstein's contributions to biomolecular sequencing through his patents and collaborations highlight his role as a leading inventor in the field. His innovative methods continue to pave the way for advancements in genetic research and diagnostics.