Peter C McCabe

Title: Innovations of Peter C McCabe in Biotechnology

Introduction

Peter C McCabe is a notable inventor based in Pittsburg, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of innovative therapeutic agents. His work focuses on the manipulation of interleukin-2, a crucial cytokine in the immune system.

Latest Patents

Peter C McCabe holds a patent for "Interleukin-2 muteins and polymer conjugation thereof." This patent involves the creation of muteins of IL-2, where one of the amino acids in the native sequence is replaced by a cysteine residue. These muteins are then conjugated to polymers such as polyethylene glycol homopolymers or polyoxyethylated polyols. The process utilizes host expression of mutant genes, which are altered through site-directed mutagenesis. This innovative approach enhances the therapeutic potential of IL-2 by improving its stability and efficacy.

Career Highlights

Peter is associated with Cetus Oncology Corporation, where he has been instrumental in advancing research in cancer therapeutics. His expertise in protein engineering and conjugation techniques has positioned him as a key figure in the development of novel biopharmaceuticals.

Collaborations

Throughout his career, Peter has collaborated with talented professionals, including Nandini Katre and Robert F Halenbeck. These collaborations have fostered a productive research environment, leading to groundbreaking advancements in the field.

Conclusion

Peter C McCabe's innovative work in the biotechnology sector, particularly with interleukin-2 muteins, showcases his commitment to advancing medical science. His contributions continue to influence the development of effective therapies for various diseases.