Peter C Gareiss

Title: Innovations by Peter C Gareiss

Introduction

Peter C Gareiss is an accomplished inventor based in Milford, CT (US). He holds 2 patents that reflect his significant contributions to the field of biochemistry and molecular biology. His work focuses on developing compounds and methods that enhance the degradation of targeted proteins and polypeptides.

Latest Patents

One of his latest patents is titled "Compounds and methods for the enhanced degradation of targeted proteins and other polypeptides by an E3 ubiquitin ligase." This invention relates to bifunctional compounds that serve as modulators of targeted ubiquitination. These compounds are particularly effective as inhibitors of various polypeptides and proteins that are degraded by the ubiquitin ligase. The invention emphasizes the importance of placing target proteins in proximity to the ubiquitin ligase to facilitate their degradation and inhibition.

Another notable patent is "MYC G-quadruplex stabilizing small molecules and their use." This patent outlines methods for treating tumors, including both benign and malignant types. The methods involve administering a small molecule that selectively binds to and stabilizes G-quadruplex DNA in the promoter of the c-MYC gene. This approach aims to decrease the size and number of metastases, showcasing the therapeutic potential of his inventions.

Career Highlights

Peter C Gareiss has worked with prestigious organizations, including Yale University and GlaxoSmithKline Intellectual Property Development Limited. His experience in these institutions has allowed him to advance his research and contribute to significant scientific advancements.

Collaborations

Throughout his career, Gareiss has collaborated with notable colleagues such as Craig M Crews and Dennis Buckley. These partnerships have likely enriched his research and led to innovative solutions in his field.

Conclusion

Peter C Gareiss is a prominent inventor whose work in developing compounds for protein degradation and tumor treatment has made a significant impact. His patents reflect a commitment to advancing scientific knowledge and improving therapeutic methods.