Perry Riggle

Title: Perry Riggle: Innovator in Eukaryotic Gene Research

Introduction

Perry Riggle is a notable inventor based in Norwood, WA (US). He has made significant contributions to the field of biotechnology, particularly in the identification of eukaryotic growth-related genes. With a total of 4 patents to his name, Riggle's work has advanced our understanding of genetic regulation in eukaryotic organisms.

Latest Patents

One of Perry Riggle's latest patents focuses on the identification of eukaryotic growth-related genes and the development of a promoter isolation vector and method of use. This invention provides a polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth. Additionally, it describes a maltose responsive promoter (MRP) isolated using the promoter library of the invention. The patent outlines a method for identifying a eukaryotic regulatory polynucleotide by complementing the growth of an auxotrophic host cell containing the vector, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome through targeted integration, and a library containing host cells with the integrated vector is also provided.

Career Highlights

Perry Riggle has had a distinguished career, working at Millennium Pharmaceuticals Limited. His innovative research has contributed to advancements in genetic engineering and biotechnology, making him a respected figure in his field.

Collaborations

Throughout his career, Riggle has collaborated with notable colleagues, including Yigal Koltin and Vicky Gavrias. These partnerships have further enhanced his research and contributions to the scientific community.

Conclusion

Perry Riggle's work in eukaryotic gene research exemplifies the impact of innovation in biotechnology. His patents and collaborations continue to influence the field, paving the way for future advancements.