Perry Newton, Iii

Title: Innovations by Perry Newton, III

Introduction

Perry Newton, III is an accomplished inventor based in Odenton, MD (US). He has made significant contributions to the field of gene therapy through his innovative methods and techniques. With a total of two patents to his name, Newton's work focuses on the purification and transduction of retroviral vectors.

Latest Patents

Newton's latest patents include a method for the purification of retroviral vectors. This method involves culturing retroviral vector producer cells capable of generating retroviral vector particles. The process includes obtaining a supernatant containing these particles, clarifying and concentrating the supernatant, and then using a precipitation agent followed by centrifugation to recover the retroviral particles. This innovative approach enhances the recovery of retroviral vector particles, which are crucial for gene therapy applications.

Another significant patent is his method of transduction of cells with retroviral vectors, known as spin transduction. This efficient method involves suspending retroviral particles in a pharmaceutically acceptable carrier and contacting them with the target cells. The mixture is then centrifuged, allowing for a substantial increase in transduction efficiency, ranging from 3 to 15 times, depending on the cell type.

Career Highlights

Newton is currently associated with Genetic Therapy, Inc., where he continues to advance his research and development in gene therapy. His work has the potential to significantly impact the treatment of various genetic disorders.

Collaborations

Newton collaborates with notable colleagues, including Hitoshi Kotani and Shuyuan Zhang, who contribute to his research endeavors.

Conclusion

Perry Newton, III is a notable inventor whose work in retroviral vector purification and transduction methods is paving the way for advancements in gene therapy. His contributions are essential for the future of medical treatments and innovations in this field.