Per-Ola Mikael Johansson

Title: Per-Ola Mikael Johansson: Innovator in Hepatitis C Research

Introduction

Per-Ola Mikael Johansson is a notable inventor based in Huddinge, Sweden. He has made significant contributions to the field of medical research, particularly in the development of inhibitors for the hepatitis C virus (HCV). With a total of nine patents to his name, Johansson's work has had a substantial impact on the treatment of this viral infection.

Latest Patents

Johansson's latest patents include innovative methods for creating HCV NS-3 serine protease inhibitors. These methods focus on peptidomimetic compounds that inhibit the NS3 protease of the hepatitis C virus. The compounds are characterized by a specific formula where variable definitions are provided in the specification. Notably, these compounds feature a carbocyclic P2 unit combined with a novel linkage that alters the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site. Another significant patent involves macrocyclic inhibitors of hepatitis C virus, which are designed to inhibit HCV replication.

Career Highlights

Throughout his career, Johansson has worked with prominent companies in the pharmaceutical industry, including Medivir AB and Janssen Sciences Ireland UC. His expertise in the field has allowed him to develop groundbreaking solutions for combating hepatitis C.

Collaborations

Johansson has collaborated with esteemed colleagues such as Kenneth Simmen and Herman Augustinus De Kock. These partnerships have further enhanced his research and innovation in the field.

Conclusion

Per-Ola Mikael Johansson's contributions to hepatitis C research through his patents and collaborations highlight his role as a leading inventor in the medical field. His work continues to pave the way for advancements in the treatment of viral infections.